![]() ![]() The infusion will take several hours, and your blood pressure, oxygen level, pulse, and breathing rate will be monitored during the process. You may have a central line, which is a large intravenous line, placed with a minor surgical procedure for the infusion. Stem cell transplantation: This process involves intravenous infusion of the stem cells.Induction is also given, which is an immune-modifying treatment to help prevent the recipient’s immune system from fighting against the transplanted cells. These treatments kill the body’s cancer cells in preparation for the transplant. Conditioning/cancer treatment: This pretransplant process includes chemotherapy and radiation.Then the cells are frozen until the transplantation takes place. These cells are collected from a donor before an allogeneic stem cell transplant, and from the recipient before an autologous transplant. Stem cell collection: The stem cells are typically collected from the blood, and sometimes from the bone marrow.However, since most people do not have an identical twin, a syngeneic transplant is rarely possible. Syngeneic transplants can lower the risk of a recipient receiving stem cells that will become cancer cells (this is a risk of autologous transplants) while reducing the risk of rejection and graft-versus-host disease (risks of allogeneic transplants). Syngeneic transplants: This is a stem cell transplant in which the donor is the identical twin of the recipient.Mini transplants: This type of allogeneic transplant uses lower-dose radiation and less toxic chemotherapy to reduce the risk of allogeneic stem cell transplant–associated complications.Tandem transplants: This is a process in which a person has multiple consecutive stem cell transplants to increase the likelihood of transplant success. Usually, the subsequent stem cell transplant is scheduled between six to 12 months after the first one.Ideally, the donor is related to the recipient, but if there is no suitable related donor, stem cells from an unrelated donor are used. Allogeneic stem cell transplant: This type of transplant uses stem cells from a donor who does not have multiple myeloma.Autologous stem cell transplant: This type of transplant uses stem cells from a person’s own body.
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